Researchers discover placental stem cells that can regenerate heart after heart attack

Researchers at the Icahn School of Medicine at Mount Sinai have demonstrated that stem cells derived from the placenta known as Cdx2 cells can regenerate healthy heart cells after heart attacks in animal models. The findings, published in the May 20 issue of Proceedings of the National Academy of Sciences (PNAS), may represent a novel treatment for regenerating the heart and other organs.

Study of Two Tribes Sheds Light on Role of Western Diet Influence’s role in Gradual Blood Pressure Rise

A South American tribe living in near-total isolation with no Western dietary influences showed no increase in average blood pressure from age one to age 60, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health. In comparison, a nearby tribe whose diet includes some processed foods and salt did show higher blood pressure into late middle age.

Rocket Pharmaceuticals Presents Preclinical Data of RP-A501 for Danon Disease at the American Society of Gene and Cell Therapy 2019 Annual Meeting

- Biodistribution of RP-A501 Demonstrates High Concentration in Heart, the End-Organ Target in Danon Disease - - Phase 1 Clinical Trial to Begin in Second Quarter of 2019 - NEW YORK, NY, USA I May 02, 2019 I Rocket Pharmaceuticals, Inc. (NASDAQ: RCKT) (“Rocket”), a leading U.S.-based multi-platform clinical-stage gene therapy company, today presents preclinical data of...

OMEICOS Therapeutics Begins Phase 2 Clinical Study Evaluating Omega 3 Metabolite in Patients with Persistent Atrial Fibrillation

OMEICOS Therapeutics, a Berlin-based biopharmaceutical company that specializes in cardiovascular and ophthalmic diseases, has announced the dosing of a first patient in a Phase 2 clinical study for the company’s Omega 3 derived metabolite, OMT-28. The study ( titled PROMISE-AF ) is a placebo-controlled, double-blind, and randomized trial designed to evaluate the efficacy, safety, and pharmacokinetics of OMT-28 in...

Diabetes drug Jardiance reverses heart failure in animal model – ketogenic diet likely provides the same benefit with less risk

Researchers at Mount Sinai Icahn School of Medicine in New York have shown in a pig model of heart failure, that after two months on the drug, markers of heart function improved dramatically. In a placebo-controlled study of 14 pigs with heart failure, cardiac magnetic resonance and 3D-echocardiography were used to observe what was happening in the animals’ hearts. They...

Anti obesity gene variant discovered – future target for treatment of obesity?

In a study published today, researchers at the Wellcome Trust-MRC institute of Metabolic Science in Cambridge appear to have identified a series of MC4R gene variants that modulate the signals in the brain that determine when the person 'feels full'. These findings solidify the idea that some people are simply 'naturally skinny'. The study covered approximately 0.5 million people in...

Tel Aviv University prints first personalized 3D heart using patient’s own cells

Researchers at Tel Aviv University have successfully printed a partially working, vascularized 3d printed heart, starting from cells obtained from a biopsy of fatty tissues. The materials from the biopsy were separated and processed into pluripotent stem cells and an extracellular matrix containing collagens, glycoproteins, and other materials which the human heart consists of. A set of hydrogel-based inks was...

Yet another bombastic diet study makes baseless claims – and the media eats it up.

Chances are that if you read any mainstream news site, you've came across a journalist's interpretation of this study from The Lancet. When i first saw this headline, i was pleased to see that a mainstream scientific publication had managed to publicise the concept that bad diet is the biggest threat to human health today. Here at...